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Trimethoprim Sulfate

CHEMBL2110367 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
678.7 g/mol
LogP
—
Phase
4

A sulfate salt form of trimethoprim with the same therapeutic properties. This antibiotic is used to treat and prevent urinary tract infections and is often combined with sulfamethoxazole (as co-trimoxazole or Bactrim) to treat a broader range of infections including certain types of pneumonia.

Khối lượng phân tử

678,7000 g/mol

TPSA

294,00 Ų

Lĩnh vực điều trị

Glaucoma Lymphoma Leukemia

Cơ chế tác dụng

Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Dihydrofolate reductase inhibitor (bacterial selective).

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/2C14H18N4O3.H2O4S/c2*1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-5(2,3)4/h2*5-7H,4H2,1-3H3,(H4,15,16,17,18);(H2,1,2,3,4)

                

                

                

                    
                    

                        
Molecular Formula

                        
C28H38N8O10S

                    

                    
                    

                        
HBD / HBA

                        
6 / 18

                    

                    
                    

                        
Liên kết có thể quay

                        
10

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
47

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A sulfate salt form of trimethoprim with the same therapeutic properties. This antibiotic is used to treat and prevent urinary tract infections and is often combined with sulfamethoxazole (as co-trimoxazole or Bactrim) to treat a broader range of infections including certain types of pneumonia.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Dihydrofolate reductase inhibitor (bacterial selective).

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Trimethoprim Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2110367.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 64936.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.