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Vigabatrin

CHEMBL89598 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
129.2 g/mol
LogP
-2.2
Phase
4

This anticonvulsant medication is used to treat infantile spasms (a severe form of epilepsy in babies) and as an add-on treatment for complex partial seizures that have not responded to other medications. It works by blocking an enzyme that breaks down GABA, increasing levels of this inhibitory neurotransmitter in the brain. A serious and irreversible side effect is progressive narrowing of peripheral vision (visual field loss), which can occur in up to one-third of patients.

Khối lượng phân tử

129,1600 g/mol

LogP

-2,20

TPSA

63,30 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Glaucoma Epilepsy Non-Alcoholic Fatty Liver Disease Obesity Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C=CC(N)CCC(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)

                

                

                

                    
                    

                        
Molecular Formula

                        
C6H11NO2

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
9

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This anticonvulsant medication is used to treat infantile spasms (a severe form of epilepsy in babies) and as an add-on treatment for complex partial seizures that have not responded to other medications. It works by blocking an enzyme that breaks down GABA, increasing levels of this inhibitory neurotransmitter in the brain. A serious and irreversible side effect is progressive narrowing of peripheral vision (visual field loss), which can occur in up to one-third of patients.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Vigabatrin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL89598.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5665.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.