Viloxazine
Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) and serotonin norepinephrine modulating agent (SNMA) that inhibits the norepinephrine transporter (NET) and also modulates multiple serotonin receptors (5-HT2B agonist, 5-HT2C antagonist), increasing prefrontal cortical norepinephrine and serotonin availability. It is approved for attention-deficit/hyperactivity disorder (ADHD) in pediatric and adult patients as a non-stimulant option. Originally developed as an antidepressant, its ADHD indication was established through later clinical trials.
Khối lượng phân tử
237,2900 g/mol
LogP
1,50
TPSA
39,70 Ų
Lipinski RO5
Đạt
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCOc1ccccc1OCC1CNCCO1
InChI
InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Molecular Formula
C13H19NO3
HBD / HBA
1 / 4
Liên kết có thể quay
5
Nguyên tử nặng
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) and serotonin norepinephrine modulating agent (SNMA) that inhibits the norepinephrine transporter (NET) and also modulates multiple serotonin receptors (5-HT2B agonist, 5-HT2C antagonist), increasing prefrontal cortical norepinephrine and serotonin availability. It is approved for attention-deficit/hyperactivity disorder (ADHD) in pediatric and adult patients as a non-stimulant option. Originally developed as an antidepressant, its ADHD indication was established through later clinical trials.
Yes, Viloxazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL306700. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5666. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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