Xanomeline Tartrate
Xanomeline tartrate is the tartrate salt form of xanomeline, a selective M1/M4 muscarinic receptor agonist being developed for schizophrenia and Alzheimer's disease. The tartrate salt form is used in the combination product with trospium chloride (KarXT/Cobenfy), where xanomeline provides central therapeutic muscarinic agonism while trospium blocks peripheral muscarinic receptors to reduce gastrointestinal side effects. This combination approach enables effective central muscarinic activation with an acceptable safety profile.
Khối lượng phân tử
431,5000 g/mol
TPSA
182,00 Ų
Lĩnh vực điều trị
Cơ chế tác dụng
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCCCCCOc1nsnc1C1=CCCN(C)C1.O=C(O)C(O)C(O)C(=O)O
InChI
InChI=1S/C14H23N3OS.C4H6O6/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12;5-1(3(7)8)2(6)4(9)10/h8H,3-7,9-11H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)
Molecular Formula
C18H29N3O7S
HBD / HBA
4 / 11
Liên kết có thể quay
10
Nguyên tử nặng
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Xanomeline tartrate is the tartrate salt form of xanomeline, a selective M1/M4 muscarinic receptor agonist being developed for schizophrenia and Alzheimer's disease. The tartrate salt form is used in the combination product with trospium chloride (KarXT/Cobenfy), where xanomeline provides central therapeutic muscarinic agonism while trospium blocks peripheral muscarinic receptors to reduce gastrointestinal side effects. This combination approach enables effective central muscarinic activation with an acceptable safety profile.
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Yes, Xanomeline Tartrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2336050. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71456. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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