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Zanamivir Hydrate

CHEMBL5315117 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
350.3 g/mol
LogP
—
Phase
4

Zanamivir hydrate is a hydrated form of zanamivir, an inhaled neuraminidase inhibitor that blocks influenza virus neuraminidase to prevent viral release and spread within the respiratory tract. The hydrate form represents a physicochemical state of the molecule used in pharmaceutical characterization and manufacturing. Clinically, it is equivalent in activity to anhydrous zanamivir for treatment and prevention of influenza infections.

Khối lượng phân tử

350,3300 g/mol

TPSA

202,00 Ų

Cơ chế tác dụng

Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)OC(C(=O)O)=C[C@@H]1NC(=N)N.O

                

                

                
                

                    
InChI

                    
InChI=1S/C12H20N4O7.H2O/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17;/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16);1H2/t5-,6+,8+,9+,10+;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H22N4O8

                    

                    
                    

                        
HBD / HBA

                        
8 / 9

                    

                    
                    

                        
Liên kết có thể quay

                        
6

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Zanamivir hydrate is a hydrated form of zanamivir, an inhaled neuraminidase inhibitor that blocks influenza virus neuraminidase to prevent viral release and spread within the respiratory tract. The hydrate form represents a physicochemical state of the molecule used in pharmaceutical characterization and manufacturing. Clinically, it is equivalent in activity to anhydrous zanamivir for treatment and prevention of influenza infections.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Inhibits viral neuraminidase, preventing the release of newly formed virus particles from infected cells and limiting viral spread within the respiratory tract.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Zanamivir Hydrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL5315117.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 636424.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.