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Zolmitriptan

CHEMBL1185 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
287.4 g/mol
LogP
2.2
Phase
4

This triptan medication is taken at the onset of a migraine headache to relieve pain, nausea, and sensitivity to light and sound. It works by stimulating serotonin receptors that cause the blood vessels in the brain to constrict and block pain signals. It is not for prevention of migraines and should not be used for hemiplegic or basilar migraines; people with cardiovascular disease should consult their doctor before use.

Khối lượng phân tử

287,3600 g/mol

LogP

2,20

TPSA

57,40 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Cardiovascular Disease Parkinson's Disease Epilepsy Migraine Multiple Sclerosis Stroke

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12

                

                

                
                

                    
InChI

                    
InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H21N3O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
Liên kết có thể quay

                        
5

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This triptan medication is taken at the onset of a migraine headache to relieve pain, nausea, and sensitivity to light and sound. It works by stimulating serotonin receptors that cause the blood vessels in the brain to constrict and block pain signals. It is not for prevention of migraines and should not be used for hemiplegic or basilar migraines; people with cardiovascular disease should consult their doctor before use.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Zolmitriptan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1185.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 60857.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.