Azithromycin vs Metronidazole

## Azithromycin vs Metronidazole: Overview

This comparison examines the pharmacological differences between **Azithromycin** and **Metronidazole**.

## Mechanism of Action

**Azithromycin**: Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis.

**Metronidazole**: Forms cytotoxic free radicals that damage bacterial DNA.

## Pharmacokinetics

**Half-life**: Azithromycin — 68 hours; Metronidazole — 8 hours.

## Chemical Properties

**Molecular Formula**: Azithromycin — C38H72N2O12; Metronidazole — C6H9N3O3.

**Molecular Weight**: Azithromycin — 748.9840 g/mol; Metronidazole — 171.1540 g/mol.

**Type**: Azithromycin — Small molecule; Metronidazole — Small molecule.