Durvalumab vs Methylprednisolone

## Durvalumab vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Methylprednisolone**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Methylprednisolone — 18-36 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Methylprednisolone — C22H30O5.

**Molecular Weight**: Durvalumab — N/A; Methylprednisolone — 374.4710 g/mol.

**Type**: Durvalumab — Antibody; Methylprednisolone — Small molecule.