Hydrochlorothiazide vs Ranitidine

## Hydrochlorothiazide vs Ranitidine: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Ranitidine**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Ranitidine**: Competitive H2 receptor antagonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Ranitidine — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Ranitidine — C13H22N4O3S.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Ranitidine — 314.4050 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Ranitidine — Small molecule.