Acyclovir Sodium
The intravenous sodium salt form of acyclovir, used in hospital settings to treat severe or life-threatening herpes virus infections, including herpes encephalitis, neonatal herpes, and severe chickenpox in immunocompromised patients. It delivers the same antiviral action as oral acyclovir but at higher concentrations achievable through the bloodstream. Adequate hydration during infusion is important to protect the kidneys from crystallization of the drug.
分子量
247.1900 g/mol
TPSA
122.00 Ų
治疗领域
作用机制
Guanosine analogue inhibiting viral DNA polymerase.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Guanosine analogue inhibiting viral DNA polymerase.
二维结构
Cite this structure
Embed this structure
SMILES
Nc1nc([O-])c2ncn(COCCO)c2n1.[Na+]
InChI
InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);/q;+1/p-1
Molecular Formula
C8H10N5NaO3
HBD / HBA
2 / 7
可旋转键数
4
重原子数
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
The intravenous sodium salt form of acyclovir, used in hospital settings to treat severe or life-threatening herpes virus infections, including herpes encephalitis, neonatal herpes, and severe chickenpox in immunocompromised patients. It delivers the same antiviral action as oral acyclovir but at higher concentrations achievable through the bloodstream. Adequate hydration during infusion is important to protect the kidneys from crystallization of the drug.
Guanosine analogue inhibiting viral DNA polymerase.
Yes, Acyclovir Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200380. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23665721. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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