Amantadine
An antiviral and dopaminergic medication with dual uses: it was originally developed to prevent influenza A infection, and it also treats the symptoms of Parkinson's disease and drug-induced movement disorders by increasing dopamine activity and blocking NMDA glutamate receptors in the brain. It can reduce involuntary movements (dyskinesias) in Parkinson's patients.
分子量
151.2500 g/mol
LogP
2.40
TPSA
26.00 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
NC12CC3CC(CC(C3)C1)C2
InChI
InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
Molecular Formula
C10H17N
HBD / HBA
1 / 1
可旋转键数
0
重原子数
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An antiviral and dopaminergic medication with dual uses: it was originally developed to prevent influenza A infection, and it also treats the symptoms of Parkinson's disease and drug-induced movement disorders by increasing dopamine activity and blocking NMDA glutamate receptors in the brain. It can reduce involuntary movements (dyskinesias) in Parkinson's patients.
Yes, Amantadine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL660. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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