Aminophylline
A combination of theophylline and ethylenediamine that relaxes the smooth muscle of the bronchi and pulmonary blood vessels, used to treat asthma and COPD by opening narrowed airways and stimulating breathing. It also has mild diuretic effects and can treat apnea in premature infants by stimulating the respiratory center in the brain.
分子量
420.4300 g/mol
TPSA
191.00 Ų
治疗领域
作用机制
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
二维结构
Cite this structure
Embed this structure
SMILES
Cn1c(=O)c2[nH]cnc2n(C)c1=O.Cn1c(=O)c2[nH]cnc2n(C)c1=O.NCCN
InChI
InChI=1S/2C7H8N4O2.C2H8N2/c2*1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h2*3H,1-2H3,(H,8,9);1-4H2
Molecular Formula
C16H24N10O4
HBD / HBA
4 / 8
可旋转键数
1
重原子数
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A combination of theophylline and ethylenediamine that relaxes the smooth muscle of the bronchi and pulmonary blood vessels, used to treat asthma and COPD by opening narrowed airways and stimulating breathing. It also has mild diuretic effects and can treat apnea in premature infants by stimulating the respiratory center in the brain.
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
Yes, Aminophylline is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1370561. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9433. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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