Amiodarone

CHEMBL633 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

645.3 g/mol

LogP

7.6

Phase

4

This heart rhythm medication works by slowing electrical signals in the heart to treat serious irregular heartbeats, including atrial fibrillation. It is typically reserved for life-threatening arrhythmias because it can affect the thyroid, lungs, and liver with long-term use, requiring regular monitoring.

分子量

645.3000 g/mol

LogP

7.60

TPSA

42.70 Å²

Lipinski 五规则

不符合

治疗领域

Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Asthma Insomnia Chronic Kidney Disease Stroke Hypertension Chronic Pain Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1

InChI

InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3

Molecular Formula

C25H29I2NO3

HBD / HBA

- / 4

可旋转键数

11

重原子数

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

This heart rhythm medication works by slowing electrical signals in the heart to treat serious irregular heartbeats, including atrial fibrillation. It is typically reserved for life-threatening arrhythmias because it can affect the thyroid, lungs, and liver with long-term use, requiring regular monitoring.

Yes, Amiodarone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL633. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2157. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C25H29I2NO3
同义词: 3

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.