Amiodarone

CHEMBL633 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

645.3 g/mol

LogP

7.6

Phase

4

This heart rhythm medication works by slowing electrical signals in the heart to treat serious irregular heartbeats, including atrial fibrillation. It is typically reserved for life-threatening arrhythmias because it can affect the thyroid, lungs, and liver with long-term use, requiring regular monitoring.

Peso Molecular

645,3000 g/mol

LogP

7,60

TPSA

42,70 Å²

Regra dos 5 de Lipinski

Reprovado

Áreas Terapêuticas

Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Asthma Insomnia Chronic Kidney Disease Stroke Hypertension Chronic Pain Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1

InChI

InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3

Molecular Formula

C25H29I2NO3

HBD / HBA

- / 4

Ligações Rotacionáveis

11

Átomos Pesados

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This heart rhythm medication works by slowing electrical signals in the heart to treat serious irregular heartbeats, including atrial fibrillation. It is typically reserved for life-threatening arrhythmias because it can affect the thyroid, lungs, and liver with long-term use, requiring regular monitoring.

Yes, Amiodarone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL633. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2157. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estrutura

Dados Rápidos

Fórmula: C25H29I2NO3
Sinônimos: 3

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.