Armodafinil
The R-enantiomer of modafinil, a wakefulness-promoting agent that is thought to work by increasing dopamine availability in the brain, helping patients stay awake. It is prescribed for excessive sleepiness associated with narcolepsy, shift work disorder, and sleep apnea.
分子量
273.4000 g/mol
LogP
1.70
TPSA
79.40 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
NC(=O)C[S@@+]([O-])C(c1ccccc1)c1ccccc1
InChI
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1
Molecular Formula
C15H15NO2S
HBD / HBA
1 / 3
可旋转键数
5
重原子数
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
The R-enantiomer of modafinil, a wakefulness-promoting agent that is thought to work by increasing dopamine availability in the brain, helping patients stay awake. It is prescribed for excessive sleepiness associated with narcolepsy, shift work disorder, and sleep apnea.
Yes, Armodafinil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201192. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9690109. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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