Brivaracetam
An anticonvulsant medication used as adjunctive therapy in adults and children with focal-onset seizures. It binds to a specific protein in nerve terminals called SV2A to modulate neurotransmitter release and reduce excessive neuronal firing. It has a rapid onset of action and is available in both oral and intravenous formulations.
分子量
212.2900 g/mol
LogP
1.00
TPSA
63.40 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
二维结构
Cite this structure
Embed this structure
SMILES
CCC[C@@H]1CC(=O)N([C@@H](CC)C(N)=O)C1
InChI
InChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1
Molecular Formula
C11H20N2O2
HBD / HBA
1 / 2
可旋转键数
5
重原子数
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An anticonvulsant medication used as adjunctive therapy in adults and children with focal-onset seizures. It binds to a specific protein in nerve terminals called SV2A to modulate neurotransmitter release and reduce excessive neuronal firing. It has a rapid onset of action and is available in both oral and intravenous formulations.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Brivaracetam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL607400. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9837243. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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