Clidinium
An anticholinergic agent that reduces stomach acid secretion and relieves gastrointestinal muscle spasms by blocking muscarinic receptors. It is often combined with a benzodiazepine to treat irritable bowel syndrome and peptic ulcers.
分子量
352.4000 g/mol
LogP
3.30
TPSA
46.50 Ų
Lipinski 五规则
符合
作用机制
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …
二维结构
Cite this structure
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SMILES
C[N+]12CCC(CC1)C(OC(=O)C(O)(c1ccccc1)c1ccccc1)C2
InChI
InChI=1S/C22H26NO3/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-11,17,20,25H,12-16H2,1H3/q+1
Molecular Formula
C22H26NO3+
HBD / HBA
1 / 3
可旋转键数
5
重原子数
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An anticholinergic agent that reduces stomach acid secretion and relieves gastrointestinal muscle spasms by blocking muscarinic receptors. It is often combined with a benzodiazepine to treat irritable bowel syndrome and peptic ulcers.
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Yes, Clidinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL620. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2784. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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