Esketamine Hydrochloride

CHEMBL2364609 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

274.2 g/mol

LogP

—

Phase

4

The hydrochloride salt form of esketamine, this fast-acting antidepressant blocks NMDA receptors in the brain to rapidly reduce severe depressive symptoms. It is administered as a nasal spray under medical supervision.

分子量

274.1800 g/mol

TPSA

29.10 Å²

治疗领域

Endometriosis Pain Management Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Major Depressive Disorder Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CN[C@]1(c2ccccc2Cl)CCCCC1=O.Cl

InChI

InChI=1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H/t13-;/m0./s1

Molecular Formula

C13H17Cl2NO

HBD / HBA

2 / 2

可旋转键数

2

重原子数

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

The hydrochloride salt form of esketamine, this fast-acting antidepressant blocks NMDA receptors in the brain to rapidly reduce severe depressive symptoms. It is administered as a nasal spray under medical supervision.

Yes, Esketamine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2364609. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 44632368. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C13H17Cl2NO
同义词: 1

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.