Esketamine Hydrochloride

CHEMBL2364609 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
274.2 g/mol
LogP
Phase
4

The hydrochloride salt form of esketamine, this fast-acting antidepressant blocks NMDA receptors in the brain to rapidly reduce severe depressive symptoms. It is administered as a nasal spray under medical supervision.

Khối lượng phân tử

274,1800 g/mol

TPSA

29,10 Ų

Lĩnh vực điều trị

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

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SMILES

CN[C@]1(c2ccccc2Cl)CCCCC1=O.Cl

InChI

InChI=1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H/t13-;/m0./s1

Molecular Formula

C13H17Cl2NO

HBD / HBA

2 / 2

Liên kết có thể quay

2

Nguyên tử nặng

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

The hydrochloride salt form of esketamine, this fast-acting antidepressant blocks NMDA receptors in the brain to rapidly reduce severe depressive symptoms. It is administered as a nasal spray under medical supervision.

Yes, Esketamine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2364609. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 44632368. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.