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Etidronic Acid

CHEMBL871 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
206.0 g/mol
LogP
-3.7
Phase
4

This bisphosphonate medication slows bone breakdown by inhibiting osteoclasts, the cells responsible for dissolving bone tissue. It is used to treat Paget's disease and to prevent bone loss in certain conditions.

分子量

206.0300 g/mol

LogP

-3.70

TPSA

135.00 Ų

Lipinski 五规则

符合

治疗领域

Osteoporosis Malaria Prostate Cancer

作用机制

Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

二维结构

SVG PNG

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SMILES

                    
CC(O)(P(=O)(O)O)P(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)

                

                

                

                    
                    

                        
Molecular Formula

                        
C2H8O7P2

                    

                    
                    

                        
HBD / HBA

                        
5 / 7

                    

                    
                    

                        
可旋转键数

                        
2

                    

                    
                    
                    

                        
重原子数

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
This bisphosphonate medication slows bone breakdown by inhibiting osteoclasts, the cells responsible for dissolving bone tissue. It is used to treat Paget's disease and to prevent bone loss in certain conditions.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Etidronic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL871.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3305.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.