Isosulfan Blue
This blue dye is injected near tumors during surgery to trace the lymphatic drainage pathway and identify sentinel lymph nodes, which are the first nodes most likely to contain cancer cells if the tumor has spread. Surgeons use this mapping technique to determine whether cancer has metastasized without removing all nearby lymph nodes.
分子量
566.7000 g/mol
TPSA
137.00 Ų
治疗领域
作用机制
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
二维结构
Cite this structure
Embed this structure
SMILES
CCN(CC)c1ccc(C(=C2C=CC(=[N+](CC)CC)C=C2)c2cc(S(=O)(=O)[O-])ccc2S(=O)(=O)[O-])cc1.[Na+]
InChI
InChI=1S/C27H32N2O6S2.Na/c1-5-28(6-2)22-13-9-20(10-14-22)27(21-11-15-23(16-12-21)29(7-3)8-4)25-19-24(36(30,31)32)17-18-26(25)37(33,34)35;/h9-19H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
Molecular Formula
C27H31N2NaO6S2
HBD / HBA
- / 7
可旋转键数
7
重原子数
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This blue dye is injected near tumors during surgery to trace the lymphatic drainage pathway and identify sentinel lymph nodes, which are the first nodes most likely to contain cancer cells if the tumor has spread. Surgeons use this mapping technique to determine whether cancer has metastasized without removing all nearby lymph nodes.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Isosulfan Blue is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200859. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 50108. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="isosulfan-blue"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/isosulfan-blue/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/isosulfan-blue/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/isosulfan-blue/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="isosulfan-blue"></drugfyi-drug>