Methsuximide
An anticonvulsant medication used to control absence seizures (brief lapses of consciousness) in patients with epilepsy who have not responded to other seizure medications. It works by reducing abnormal electrical activity in the brain.
分子量
203.2400 g/mol
LogP
1.20
TPSA
37.40 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
二维结构
Cite this structure
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SMILES
CN1C(=O)CC(C)(c2ccccc2)C1=O
InChI
InChI=1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,1-2H3
Molecular Formula
C12H13NO2
HBD / HBA
- / 2
可旋转键数
1
重原子数
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
An anticonvulsant medication used to control absence seizures (brief lapses of consciousness) in patients with epilepsy who have not responded to other seizure medications. It works by reducing abnormal electrical activity in the brain.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Methsuximide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL697. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6476. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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