Rimantadine

CHEMBL959 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

179.3 g/mol

LogP

2.6

Phase

4

Rimantadine is an adamantane antiviral agent structurally related to amantadine that inhibits the M2 ion channel of influenza A virus, blocking the hydrogen ion influx required for viral uncoating and preventing release of viral RNA into the host cell cytoplasm. It is used for prophylaxis and treatment of influenza A infections, though widespread resistance among circulating influenza A strains has significantly limited its clinical utility.

分子量

179.3000 g/mol

LogP

2.60

TPSA

26.00 Å²

Lipinski 五规则

符合

治疗领域

Respiratory Disease Asthma Chronic Obstructive Pulmonary Disease Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CC(N)C12CC3CC(CC(C3)C1)C2

InChI

InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3

Molecular Formula

C12H21N

HBD / HBA

1 / 1

可旋转键数

1

重原子数

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Rimantadine is an adamantane antiviral agent structurally related to amantadine that inhibits the M2 ion channel of influenza A virus, blocking the hydrogen ion influx required for viral uncoating and preventing release of viral RNA into the host cell cytoplasm. It is used for prophylaxis and treatment of influenza A infections, though widespread resistance among circulating influenza A strains has significantly limited its clinical utility.

Yes, Rimantadine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL959. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5071. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C12H21N
同义词: 1

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.