Rosiglitazone Maleate

CHEMBL843 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

473.5 g/mol

LogP

—

Phase

4

The maleate salt formulation of rosiglitazone used to improve blood sugar control in type 2 diabetes by activating PPAR-gamma receptors that regulate glucose and fat metabolism. It is used with caution and close monitoring due to potential cardiovascular risks.

分子量

473.5000 g/mol

TPSA

171.00 Å²

治疗领域

Bladder Cancer Thyroid Cancer Endometriosis Cardiovascular Disease Respiratory Disease Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Schizophrenia Bipolar Disorder Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Malaria HIV/AIDS Hepatitis C Heart Failure Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1.O=C(O)/C=C\C(=O)O

InChI

InChI=1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-

Molecular Formula

C22H23N3O7S

HBD / HBA

3 / 10

可旋转键数

9

重原子数

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

The maleate salt formulation of rosiglitazone used to improve blood sugar control in type 2 diabetes by activating PPAR-gamma receptors that regulate glucose and fat metabolism. It is used with caution and close monitoring due to potential cardiovascular risks.

Yes, Rosiglitazone Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL843. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5281055. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C22H23N3O7S
同义词: 2

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.