Sodium Iodide I 131
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
分子量
153.8959 g/mol
TPSA
0.00 Ų
治疗领域
作用机制
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
二维结构
Cite this structure
Embed this structure
SMILES
[131I-].[Na+]
InChI
InChI=1S/HI.Na/h1H;/q;+1/p-1/i1+4;
Molecular Formula
INa
HBD / HBA
- / 1
可旋转键数
0
重原子数
2
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Yes, Sodium Iodide I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201084. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71368. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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