Sulindac

CHEMBL15770 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

356.4 g/mol

LogP

3.4

Phase

4

A non-steroidal anti-inflammatory drug that reduces pain and inflammation by inhibiting prostaglandin production, used for arthritis, acute gout, and other musculoskeletal pain conditions. Research has also explored its potential to inhibit the growth of colon and other cancer cells through additional mechanisms beyond COX inhibition.

分子量

356.4000 g/mol

LogP

3.40

TPSA

73.60 Å²

Lipinski 五规则

符合

治疗领域

Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Pain Management Non-Small Cell Lung Cancer Hypertension Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc([S+](C)[O-])cc1

InChI

InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-

Molecular Formula

C20H17FO3S

HBD / HBA

1 / 5

可旋转键数

4

重原子数

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A non-steroidal anti-inflammatory drug that reduces pain and inflammation by inhibiting prostaglandin production, used for arthritis, acute gout, and other musculoskeletal pain conditions. Research has also explored its potential to inhibit the growth of colon and other cancer cells through additional mechanisms beyond COX inhibition.

Yes, Sulindac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL15770. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 1548887. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C20H17FO3S

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.