Thallous Chloride Tl 201
Thallous chloride Tl 201 is a radioactive potassium analog that is taken up by viable myocardial cells via the Na+/K+-ATPase pump proportional to regional myocardial blood flow and cellular viability, historically used as the primary myocardial perfusion imaging agent for detection of coronary artery disease by SPECT. The 201Tl emits mercury x-rays and gamma photons (167 keV) detectable by gamma camera. Its redistribution property over time allows distinction of ischemic (reversible perfusion defect) from infarcted (fixed defect) myocardium in a single injection rest-redistribution protocol.
分子量
236.4200 g/mol
TPSA
0.00 Ų
Pharmacokinetics (PK)
Pharmacodynamics (PD)
SMILES
Cl[201Tl]
InChI
InChI=1S/ClH.Tl/h1H;/q;+1/p-1/i;1-3
Molecular Formula
ClTl
HBD / HBA
- / -
可旋转键数
0
重原子数
2
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Thallous chloride Tl 201 is a radioactive potassium analog that is taken up by viable myocardial cells via the Na+/K+-ATPase pump proportional to regional myocardial blood flow and cellular viability, historically used as the primary myocardial perfusion imaging agent for detection of coronary artery disease by SPECT. The 201Tl emits mercury x-rays and gamma photons (167 keV) detectable by gamma camera. Its redistribution property over time allows distinction of ischemic (reversible perfusion defect) from infarcted (fixed defect) myocardium in a …
Yes, Thallous Chloride Tl 201 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200535. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 16019977. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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