Ticlopidine
This antiplatelet medication reduces the risk of stroke in patients who have had a previous stroke or TIA (mini-stroke) and cannot take aspirin. It works by blocking ADP-mediated platelet aggregation, preventing blood clots from forming. Its use has declined due to serious side effects including low white blood cell count and a rare but dangerous blood disorder (TTP), and it has largely been replaced by newer agents.
分子量
263.8000 g/mol
LogP
3.60
TPSA
31.50 Ų
Lipinski 五规则
符合
治疗领域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
二维结构
Cite this structure
Embed this structure
SMILES
Clc1ccccc1CN1CCc2sccc2C1
InChI
InChI=1S/C14H14ClNS/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14/h1-4,6,8H,5,7,9-10H2
Molecular Formula
C14H14ClNS
HBD / HBA
- / 2
可旋转键数
2
重原子数
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
This antiplatelet medication reduces the risk of stroke in patients who have had a previous stroke or TIA (mini-stroke) and cannot take aspirin. It works by blocking ADP-mediated platelet aggregation, preventing blood clots from forming. Its use has declined due to serious side effects including low white blood cell count and a rare but dangerous blood disorder (TTP), and it has largely been replaced by newer agents.
Yes, Ticlopidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL833. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5472. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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