Antagonist
A substance that binds to a receptor without activating it, blocking the action of endogenous ligands or agonists. Competitive antagonists can be overcome by increased agonist; irreversible antagonists cannot.
示例
- Naloxone (opioid antagonist)
- Propranolol (beta-blocker)
- Losartan (AT1 antagonist)
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A substance that binds to a receptor without activating it, blocking the action of endogenous ligands or agonists. Competitive antagonists can be overcome by increased agonist; irreversible antagonists cannot.