Immunosuppressant
A drug that suppresses or reduces the activity of the immune system, used primarily to prevent organ transplant rejection and to treat autoimmune diseases. Immunosuppressants act through diverse mechanisms including T-cell inhibition, cytokine blockade, and lymphocyte depletion. Multi-drug regimens are standard to minimize toxicity of individual agents.
示例
- Cyclosporine — calcineurin inhibitor (transplant rejection)
- Mycophenolate mofetil — IMPDH inhibitor (transplant, lupus nephritis)
- Azathioprine — purine antimetabolite (autoimmune diseases)
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A drug that suppresses or reduces the activity of the immune system, used primarily to prevent organ transplant rejection and to treat autoimmune diseases. Immunosuppressants act through diverse mechanisms including …