Time to Maximum Concentration (Tmax)
TmaxThe time elapsed between drug administration and the point of maximum plasma concentration (Cmax). Reflects the rate of absorption and is independent of dose for linear PK systems.
示例
- Tmax delayed by food
- ER formulations have later Tmax
- IV bolus: Tmax = 0
您知道吗？
The time elapsed between drug administration and the point of maximum plasma concentration (Cmax). Reflects the rate of absorption and is independent of dose for linear PK systems.