Cyproheptadine Hydrochloride

CHEMBL1716 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
323.9 g/mol
LogP
Phase
4

The hydrochloride salt of cyproheptadine, an antihistamine with antiserotonin effects used for allergic conditions and appetite stimulation. It causes sedation and may be used as a sleep aid in some patients.

الوزن الجزيئي

323,9000 g/mol

TPSA

3,20 Ų

المجالات العلاجية

آلية العمل

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

البنية ثنائية الأبعاد

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SMILES

CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1.Cl

InChI

InChI=1S/C21H21N.ClH/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;/h2-11H,12-15H2,1H3;1H

Molecular Formula

C21H22ClN

HBD / HBA

1 / 1

الروابط القابلة للدوران

0

الذرات الثقيلة

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

The hydrochloride salt of cyproheptadine, an antihistamine with antiserotonin effects used for allergic conditions and appetite stimulation. It causes sedation and may be used as a sleep aid in some patients.

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Yes, Cyproheptadine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1716. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 13770. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.