Cyproheptadine Hydrochloride
The hydrochloride salt of cyproheptadine, an antihistamine with antiserotonin effects used for allergic conditions and appetite stimulation. It causes sedation and may be used as a sleep aid in some patients.
Peso Molecular
323,9000 g/mol
TPSA
3,20 Ų
Áreas Terapêuticas
Mecanismo de Ação
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1.Cl
InChI
InChI=1S/C21H21N.ClH/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;/h2-11H,12-15H2,1H3;1H
Molecular Formula
C21H22ClN
HBD / HBA
1 / 1
Ligações Rotacionáveis
0
Átomos Pesados
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
The hydrochloride salt of cyproheptadine, an antihistamine with antiserotonin effects used for allergic conditions and appetite stimulation. It causes sedation and may be used as a sleep aid in some patients.
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Yes, Cyproheptadine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1716. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 13770. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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