Sodium Monofluorophosphate
Sodium monofluorophosphate is a fluoride compound used as an active ingredient in fluoride toothpastes for caries prevention, releasing fluoride ions after enzymatic hydrolysis in the oral cavity to promote remineralization of tooth enamel. Unlike sodium fluoride, it requires hydrolysis by salivary phosphatases before fluoride ions become bioavailable for enamel incorporation. It is widely used in oral hygiene products as an alternative fluoride source.
الوزن الجزيئي
143,9500 g/mol
TPSA
63,20 Ų
آلية العمل
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
O=P([O-])([O-])F.[Na+].[Na+]
InChI
InChI=1S/FH2O3P.2Na/c1-5(2,3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
Molecular Formula
FNa2O3P
HBD / HBA
- / 4
الروابط القابلة للدوران
0
الذرات الثقيلة
7
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
Sodium monofluorophosphate is a fluoride compound used as an active ingredient in fluoride toothpastes for caries prevention, releasing fluoride ions after enzymatic hydrolysis in the oral cavity to promote remineralization of tooth enamel. Unlike sodium fluoride, it requires hydrolysis by salivary phosphatases before fluoride ions become bioavailable for enamel incorporation. It is widely used in oral hygiene products as an alternative fluoride source.
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.
Yes, Sodium Monofluorophosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1908359. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24266. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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