Dequalinium

CHEMBL333826 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
456.7 g/mol
LogP
7.3
Phase
4

A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.

Molekularmasse

456,7000 g/mol

LogP

7,30

TPSA

59,80 Ų

Lipinski-Regel der Fünf

Bestanden

Wirkmechanismus

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

2D-Struktur

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SMILES

Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21

InChI

InChI=1S/C30H38N4/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3/p+2

Molecular Formula

C30H40N4+2

HBD / HBA

2 / 2

Rotierbare Bindungen

11

Schwere Atome

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Yes, Dequalinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL333826. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2993. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.