Dequalinium
A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.
Molekularmasse
456,7000 g/mol
LogP
7,30
TPSA
59,80 Ų
Lipinski-Regel der Fünf
Bestanden
Wirkmechanismus
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
2D-Struktur
Cite this structure
Embed this structure
SMILES
Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21
InChI
InChI=1S/C30H38N4/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3/p+2
Molecular Formula
C30H40N4+2
HBD / HBA
2 / 2
Rotierbare Bindungen
11
Schwere Atome
34
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Yes, Dequalinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL333826. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2993. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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