Dequalinium
A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.
Moleküler Ağırlık
456,7000 g/mol
LogP
7,30
TPSA
59,80 Ų
Lipinski RO5
Geçer
Etki Mekanizması
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
2D Yapı
Cite this structure
Embed this structure
SMILES
Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21
InChI
InChI=1S/C30H38N4/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3/p+2
Molecular Formula
C30H40N4+2
HBD / HBA
2 / 2
Döndürülebilir Bağlar
11
Ağır Atomlar
34
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.
Yes, Dequalinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL333826. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2993. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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