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Dequalinium

CHEMBL333826 Phase 4 Approuvé Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
456.7 g/mol
LogP
7.3
Phase
4

A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.

Masse moléculaire

456,7000 g/mol

LogP

7,30

TPSA

59,80 Ų

Règle des 5 de Lipinski

Conforme

Mécanisme d'action

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21

                

                

                
                

                    
InChI

                    
InChI=1S/C30H38N4/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3/p+2

                

                

                

                    
                    

                        
Molecular Formula

                        
C30H40N4+2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
Liaisons Rotatives

                        
11

                    

                    
                    
                    

                        
Atomes Lourds

                        
34

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
A quaternary ammonium compound with antiseptic and antifungal properties used topically as lozenges for oral and throat infections and as vaginal tablets for bacterial vaginosis. It disrupts microbial cell membranes and has a broad spectrum of antimicrobial activity.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Dequalinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL333826.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2993.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.