Dimercaprol

CHEMBL1597 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
124.2 g/mol
LogP
0.2
Phase
4

A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.

Molekularmasse

124,2300 g/mol

LogP

0,20

TPSA

22,20 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Wirkmechanismus

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

2D-Struktur

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SMILES

OCC(S)CS

InChI

InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2

Molecular Formula

C3H8OS2

HBD / HBA

3 / 3

Rotierbare Bindungen

2

Schwere Atome

6

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Yes, Dimercaprol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1597. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 3080. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.