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Dimercaprol

CHEMBL1597 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
124.2 g/mol
LogP
0.2
Phase
4

A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.

Молекулярная масса

124,2300 g/mol

LogP

0,20

TPSA

22,20 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Respiratory Disease Pain Management Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Infectious Disease Gastroesophageal Reflux Disease Systemic Lupus Erythematosus Multiple Sclerosis Stroke Lymphoma Breast Cancer Chronic Pain HIV/AIDS Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Механизм действия

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
OCC(S)CS

                

                

                
                

                    
InChI

                    
InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C3H8OS2

                    

                    
                    

                        
HBD / HBA

                        
3 / 3

                    

                    
                    

                        
Вращаемые Связи

                        
2

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
6

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Dimercaprol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1597.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3080.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.