Sulfisomidine

CHEMBL485696 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

278.3 g/mol

LogP

1.2

Phase

4

Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

Molekularmasse

278,3300 g/mol

LogP

1,20

TPSA

106,00 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1

InChI

InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

Molecular Formula

C12H14N4O2S

HBD / HBA

2 / 6

Rotierbare Bindungen

3

Schwere Atome

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Sulfisomidine (sulfaisodimidine) is a short-acting sulfonamide antibiotic with good urinary solubility used for urinary tract infections and other susceptible bacterial infections, offering a lower risk of crystalluria than older sulfonamides due to its better aqueous solubility. Like all sulfonamides, it competitively inhibits dihydropteroate synthase to block bacterial folic acid synthesis. Its clinical use has declined with the emergence of sulfonamide resistance.

Yes, Sulfisomidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL485696. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5343. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C12H14N4O2S

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.