Sulfur Hexafluoride

CHEMBL1796998 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
146.1 g/mol
LogP
4.2
Phase
4

Sulfur hexafluoride is a chemically inert, non-toxic gas used as an ultrasound contrast agent (SonoVue/Lumason) encapsulated in phospholipid microbubbles to enhance echocardiographic imaging of cardiac structures and vascularity of focal liver lesions and other organs. The microbubbles oscillate resonantly under ultrasound insonation, dramatically increasing acoustic backscatter from blood pool to improve contrast between vasculature and surrounding tissue. It is also used in ophthalmology as a vitreous tamponade for retinal detachment repair.

Molekularmasse

146,0600 g/mol

LogP

4,20

TPSA

1,00 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Wirkmechanismus

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

2D-Struktur

SVG PNG

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SMILES

FS(F)(F)(F)(F)F

InChI

InChI=1S/F6S/c1-7(2,3,4,5)6

Molecular Formula

F6S

HBD / HBA

- / 6

Rotierbare Bindungen

0

Schwere Atome

7

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Sulfur hexafluoride is a chemically inert, non-toxic gas used as an ultrasound contrast agent (SonoVue/Lumason) encapsulated in phospholipid microbubbles to enhance echocardiographic imaging of cardiac structures and vascularity of focal liver lesions and other organs. The microbubbles oscillate resonantly under ultrasound insonation, dramatically increasing acoustic backscatter from blood pool to improve contrast between vasculature and surrounding tissue. It is also used in ophthalmology as a vitreous tamponade for retinal detachment repair.

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Yes, Sulfur Hexafluoride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1796998. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 17358. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.