Prodrug

Chemistry

A pharmacologically inactive compound that is metabolically converted to an active drug in vivo. Used to improve bioavailability, reduce toxicity, or target specific tissues.

Beispiele

Enalapril -> enalaprilat
Codeine -> morphine (CYP2D6)
Valacyclovir -> acyclovir

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A pharmacologically inactive compound that is metabolically converted to an active drug in vivo. Used to improve bioavailability, reduce toxicity, or target specific tissues.