GABRA1 (GABA-A Receptor)
GABRA1
Ligand-gated chloride channel mediating fast inhibitory neurotransmission in the CNS.
Funktion
Benzodiazepines, barbiturates, and general anesthetics enhance GABA-A receptor function via allosteric modulation.
Arzneimittel, die auf dieses Target wirken
| Arzneimittel | Wirkung | Primär |
|---|---|---|
| Diazepam | Agonist | Ja |
| Alprazolam | Agonist | Ja |
| Zolpidem | Agonist | Ja |
| Memantine | Antagonist | Ja |
| Valproic Acid | Agonist | — |
| Topiramate | Agonist | — |