GABRA1 (GABA-A Receptor)
GABRA1
Ligand-gated chloride channel mediating fast inhibitory neurotransmission in the CNS.
Function
Benzodiazepines, barbiturates, and general anesthetics enhance GABA-A receptor function via allosteric modulation.
Drugs Acting on This Target
| Drug | Action | Primary |
|---|---|---|
| Diazepam | Agonist | Yes |
| Alprazolam | Agonist | Yes |
| Zolpidem | Agonist | Yes |
| Memantine | Antagonist | Yes |
| Valproic Acid | Agonist | — |
| Topiramate | Agonist | — |