SLC6A4 (Serotonin Transporter)

SLC6A4

Sodium-dependent serotonin transporter responsible for reuptake of 5-HT from the synaptic cleft.

Funktion

Primary target for SSRIs and SNRIs. Inhibition increases synaptic serotonin.

Arzneimittel, die auf dieses Target wirken

Arzneimittel Wirkung Primär
Sertraline Inhibitor Ja
Escitalopram Inhibitor Ja
Fluoxetine Inhibitor Ja
Duloxetine Inhibitor Ja
Venlafaxine Inhibitor Ja
Tramadol Inhibitor Ja
Ondansetron Other Ja
Quetiapine Inhibitor
Bupropion Inhibitor
Trazodone Inhibitor
Sumatriptan Other
Aripiprazole Partial Agonist

Related Targets