Cholecalciferol
The naturally occurring form of vitamin D3, produced in the skin upon exposure to ultraviolet B radiation or obtained from dietary sources and supplements, which is converted in the body to the biologically active form calcitriol. It is essential for calcium and phosphate homeostasis, bone metabolism, and immune function. Supplementation is widely recommended for individuals with inadequate sun exposure or dietary intake.
Molecular Weight
384.6000 g/mol
LogP
7.90
TPSA
20.20 Ų
Lipinski RO5
Pass
Therapeutic Areas
Mechanism of Action
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
2D Structure
Cite this structure
Embed this structure
SMILES
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@H]12
InChI
InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
Molecular Formula
C27H44O
HBD / HBA
1 / 1
Rotatable Bonds
6
Heavy Atoms
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
The naturally occurring form of vitamin D3, produced in the skin upon exposure to ultraviolet B radiation or obtained from dietary sources and supplements, which is converted in the body to the biologically active form calcitriol. It is essential for calcium and phosphate homeostasis, bone metabolism, and immune function. Supplementation is widely recommended for individuals with inadequate sun exposure or dietary intake.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Cholecalciferol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1042. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5280795. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="cholecalciferol"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/cholecalciferol/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/cholecalciferol/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/cholecalciferol/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="cholecalciferol"></drugfyi-drug>