Cholecalciferol

CHEMBL1042 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
384.6 g/mol
LogP
7.9
Phase
4

The naturally occurring form of vitamin D3, produced in the skin upon exposure to ultraviolet B radiation or obtained from dietary sources and supplements, which is converted in the body to the biologically active form calcitriol. It is essential for calcium and phosphate homeostasis, bone metabolism, and immune function. Supplementation is widely recommended for individuals with inadequate sun exposure or dietary intake.

Peso Molecular

384,6000 g/mol

LogP

7,90

TPSA

20,20 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Mecanismo de Ação

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Estrutura 2D

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@H]12

InChI

InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1

Molecular Formula

C27H44O

HBD / HBA

1 / 1

Ligações Rotacionáveis

6

Átomos Pesados

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The naturally occurring form of vitamin D3, produced in the skin upon exposure to ultraviolet B radiation or obtained from dietary sources and supplements, which is converted in the body to the biologically active form calcitriol. It is essential for calcium and phosphate homeostasis, bone metabolism, and immune function. Supplementation is widely recommended for individuals with inadequate sun exposure or dietary intake.

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Yes, Cholecalciferol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1042. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5280795. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.