Hetacillin Potassium
A potassium salt form of hetacillin, a penicillin-class antibiotic prodrug that is converted to ampicillin in the body to treat bacterial infections. The potassium salt improves solubility for pharmaceutical formulations. It is used for the treatment of infections caused by susceptible gram-positive and gram-negative bacteria.
Molecular Weight
427.6000 g/mol
TPSA
118.00 Ų
Mechanism of Action
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
2D Structure
Cite this structure
Embed this structure
SMILES
CC1(C)S[C@@H]2[C@H](N3C(=O)[C@@H](c4ccccc4)NC3(C)C)C(=O)N2[C@H]1C(=O)[O-].[K+]
InChI
InChI=1S/C19H23N3O4S.K/c1-18(2)13(17(25)26)21-15(24)12(16(21)27-18)22-14(23)11(20-19(22,3)4)10-8-6-5-7-9-10;/h5-9,11-13,16,20H,1-4H3,(H,25,26);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1
Molecular Formula
C19H22KN3O4S
HBD / HBA
1 / 6
Rotatable Bonds
3
Heavy Atoms
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A potassium salt form of hetacillin, a penicillin-class antibiotic prodrug that is converted to ampicillin in the body to treat bacterial infections. The potassium salt improves solubility for pharmaceutical formulations. It is used for the treatment of infections caused by susceptible gram-positive and gram-negative bacteria.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Hetacillin Potassium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201121. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23678597. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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