Sodium Gluconate

CHEMBL2068884 Phase 4 Approved Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
218.1 g/mol
LogP
Phase
4

Sodium gluconate is a sodium salt of gluconic acid used primarily as an electrolyte and pH-buffering agent in pharmaceutical formulations, dialysate solutions, and as an iron chelator precursor. It provides a readily metabolizable organic anion that can be used as an alkalinizing agent in parenteral solutions, offering gentler alkalinization than bicarbonate. It has also been used in bladder irrigation solutions and investigated for mineral supplementation.

Molecular Weight

218.1400 g/mol

TPSA

141.00 Ų

Therapeutic Areas

Mechanism of Action

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

2D Structure

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SMILES

O=C([O-])[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O.[Na+]

InChI

InChI=1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1/t1-,2-,3+,4-,6-;/m0./s1

Molecular Formula

C6H11NaO7

HBD / HBA

5 / 7

Rotatable Bonds

5

Heavy Atoms

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Sodium gluconate is a sodium salt of gluconic acid used primarily as an electrolyte and pH-buffering agent in pharmaceutical formulations, dialysate solutions, and as an iron chelator precursor. It provides a readily metabolizable organic anion that can be used as an alkalinizing agent in parenteral solutions, offering gentler alkalinization than bicarbonate. It has also been used in bladder irrigation solutions and investigated for mineral supplementation.

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Yes, Sodium Gluconate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2068884. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 23672301. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.