Succinylcholine Chloride
Succinylcholine chloride is a depolarizing neuromuscular blocking agent used for rapid sequence intubation and tracheal intubation as an adjunct to anesthesia, acting as a nicotinic acetylcholine receptor agonist that causes sustained depolarization of the motor end plate, resulting in initial fasciculations followed by flaccid paralysis. Its extremely rapid onset (60 seconds) and short duration (10-15 minutes) due to hydrolysis by plasma cholinesterase make it the agent of choice for emergency intubation. It must be used with great caution in patients with hyperkalemia risk.
Molecular Weight
361.3000 g/mol
TPSA
52.60 Ų
Therapeutic Areas
Mechanism of Action
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
2D Structure
Cite this structure
Embed this structure
SMILES
C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]
InChI
InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
Molecular Formula
C14H30Cl2N2O4
HBD / HBA
- / 6
Rotatable Bonds
11
Heavy Atoms
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Succinylcholine chloride is a depolarizing neuromuscular blocking agent used for rapid sequence intubation and tracheal intubation as an adjunct to anesthesia, acting as a nicotinic acetylcholine receptor agonist that causes sustained depolarization of the motor end plate, resulting in initial fasciculations followed by flaccid paralysis. Its extremely rapid onset (60 seconds) and short duration (10-15 minutes) due to hydrolysis by plasma cholinesterase make it the agent of choice for emergency intubation. It must be used with great caution in patients …
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.
Yes, Succinylcholine Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL983. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 22475. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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